ARVO 2015: My first international conference!

This year’s ARVO conference was in Denver, Colorado. I was very excited; I’d never been to the States, or to a big conference. It was great, but I wish I had more time to see everything! I presented RNAseq GSEA data showing that structural and metabolic pathways are correlated with the eye size during myopia and hyperopia induction in chicks. Here’s my obligatory awkward first conference poster pic (and a great snap I took of the view near Estes Park, a few hours’ drive from Denver). For a better look at my poster click here.

Welcome

I’m a PhD candidate at La Trobe University in Melbourne. I completed my undergrad degree in Psychological Science, and I’m now delving into the exciting world of biology and ‘omic data’. My research focuses on investigating the biological mechanisms underlying ocular growth control and the development of myopia (short-sightedness). With my submission date (almost) in sight, I’ve started this blog to chronicle my successes and failures as I explore ways to analyse, interpret, and display my data.

For more about my research, check out ResearchGate or click on the publication links below.



Publications
Murphy, M., Riddell, N., Crewther, D.P., Simpson, D., & Crewther, S.G. (2018). Temporal whole field sawtooth flicker without a spatial component elicits a myopic shift following optical defocus irrespective of waveform direction in chicks. PeerJ, 7, e6277.

Giummarra, L., Crewther, S.G., Riddell, N., Murphy, M., & Crewther, D.P. (2018). Pathway analysis identifies altered mitochondrial metabolism, neurotransmission, structural pathways and complement cascade in retina/RPE/choroid in chick model of form-deprivation myopia. PeerJ, 6, e5048.

Riddell, N., Faou, P., Crewther, S.G. (2018). Short term optical defocus perturbs normal developmental shifts in retina/RPE protein abundance. BMC Developmental Biology, 18, 18.

Riddell, N., Faou, P., Murphy, M., Giummarra, L., Downs, R., & Crewther, S.G. (2017). The retina/RPE proteome in chick myopia and hyperopia models: commonalities with inherited and age-related ocular pathologies. Molecular Vision, 23, 872-888.

Riddell, N., & Crewther, S. G. (2017). Novel evidence for complement system activation in chick myopia and hyperopia models: a meta-analysis of transcriptome datasets. Scientific Reports, 7, 9719.

Riddell, N., & Crewther, S. G. (2017). Integrated comparison of GWAS, transcriptome, and proteomics studies highlights similarities in the biological basis of animal and human myopia. Investigative Ophthalmology & Visual Science, 58(1), 660-669.

Riddell, N., Giummarra, L., Hall, N. E., & Crewther, S. G. (2016). Bidirectional expression of metabolic, structural, and immune pathways in early myopia and hyperopia. Frontiers in Neuroscience, 10.

Riddell, N., Hugrass, L., Jayasuriya, J., Crewther, S. G., & Crewther, D. P. (2016). An asymmetric outer retinal response to drifting sawtooth gratings. Journal of Neurophysiology, 115(5), 2349-2358.